ISSN:
1573-739X
Keywords:
Chromatography, high pressure liquid
;
Clearance
;
Metabolism
;
Pharmacokinetics
;
Sulfaphenazole
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A direct high pressure liquid chromatographic analysis of sulfaphenazole-N2-glucuronide in urine is described. After an oral dose of 439 mg of sulfaphenazole, 0% is excreted unchanged in the urine, 〈 1% is excreted as N4-acetylsulfaphenazole. As N2-glucuronide 49.4% is excreted in one slow acetylator and 84.8% in one fast acetylator.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01967825