ISSN:
1573-9171
Keywords:
2-(2-cyanoaziridino)-2-(2-carbamoylaziridino)propane
;
l-tert-butyl-2-carbamoylaziridine
;
α-1-aziridinoalkylation
;
1H and13C NMR spectra
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The structure of azimexone (3), the product of the reaction of 2-cyanoaziridine with acetone, was confirmed on the basis of1H and13C NMR spectra. The formation of this product is accounted for by the α-aziridinoalkylating action of an intermediate containing a good leaving iminoyloxy group. Similar reactions were observed for 1-chloromethylaziridine and a 1-aziridinylmethylammonium salt (6), but not for 1-methoxymethylaziridine (7) and 1-aziridinemethanol.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00698898