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CROSS-PRESENTATION, DENDRITIC CELLS, TOLERANCE AND IMMUNITY (2001)

Heath, William R. ; Carbone, Francis R.

Palo Alto, Calif. : Annual Reviews

Annual Review of Immunology 19 (2001), S. 47-64

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ISSN: 0732-0582

Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff

Topics: Biology , Medicine

Notes: Abstract This review examines the role of cross-presentation in tolerance and immunity. We discuss (a) the antigenic requirements for cross-presentation, (b) the phenotype of the antigen presenting cell (APC), (c) the cellular interactions and molecular signals involved in cross-priming, and (d) the factors that direct the immune system toward tolerance or immunity. A large part of this review is dedicated to summarizing our current knowledge of the cross-presenting APC.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1146/annurev.immunol.19.1.47

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