ISSN:
0021-8383
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Non Steroidal Antiinflammatory Agents. V. Basic Esters of IndometacinThe reaction of diisopropylcarbodiimid 1a with ethanolamines 2a, b affords isoureas 3a, b which in turn react with indometacin 4 to yield the title compounds 6a, b. The noncatalyzed reaction of 1a, b with 4 (also in the presence of 2) leads to the ureido-indometacines 8a, b.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/prac.19903320408