Wiley InterScience Backfile Collection 1832-2000
Chemistry and Pharmacology
On the Regio- and Stereoselectivity of Nucleophilic Thiol Additions to PolyinesNucleophilic thiophenol additions to α,ω-diphenyl polyines Ph-(C≡C)n-Ph (n = 2-4) (1-3) take a regio- and stereoselective course. The well-defined, crystalline addition products bind the phenylthio group in terminal position of the aliphatic chain, the resulting C, C-double bonds of the mono-(4, 6, 8) and bis-addition products (5, 7, 9) are (Z)-configurated, as unequivocally proved by 13C-n.m.r. analysis.
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