ISSN:
1434-193X
Keywords:
DNA recognition
;
Oligonucleotides
;
Solid-phase synthesis
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
An improved protocol for the synthesis of oligonucleotides containing a 3′-3′ phosphodiester linkage, for use in an alternate strand triple-helix formation approach, is reported. Three 16-mers and one 24-mer have been efficiently synthesized and the corresponding triplexes have been analyzed by thermal denaturation experiments and CD spectroscopy.
Type of Medium:
Electronic Resource