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  • 1
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Cell Motility and the Cytoskeleton 2 (1982), S. 333-341 
    ISSN: 0886-1544
    Keywords: cell motility ; collagen ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The motility of an epithelial cell line NBT-II derived from a rat bladder tumor was examined on glass and on collagen. On glass the cells rotate in groups of 2-8 cells. Rotatory migration ceases as cells enter into mitosis; after mitosis, the daughter cells spread out and participate in the rotatory activity of the group. As the number of cells in a group increases the rate of rotatory migration slows, and groups with ten cells or more do not rotate consistently. On collagen NBT-II cells migrate as single cells in a smooth gliding fashion, with the broad lamellipodia as the leading front. After mitosis, the two daughter cells separate at 180° of each other and migrate away independently. Before totally spreading out on the collagen surface, the pair of daughter cells shows a characteristic twist of about 60° from their original position at telophase. The difference in motility of NBT II cells on glass and on collagen is explained in terms of differences in cell-to-cell cohesion and cell-to-substrate adhesion.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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