ISSN:
0749-1581
Keywords:
Transient NOE experiments
;
Synchronous nutation experiments
;
NAD stack interactions
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Cross-relaxation interactions between the nicotinamide moiety and the adenine moiety of NAD in D2O solution were unambiguously revealed by steady-state NOE experiments, transient NOE experiments and synchronous nutation experiments. The experimental results, which allow a concise description in terms of auto-relaxation and cross-relaxation, are interpreted as the result of a stacking interaction. Studies of 13C relaxation and investigations on ternary mixtures with 6-methylpurine give evidence for an inter- rather than intra-molecular stack interaction, at least in the NMR concentration range.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260301304
