ISSN:
0749-1581
Keywords:
NMR
;
Relaxation
;
Selective pulses
;
Distance
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
An efficient method of measuring proton spin-lattice cross-relaxation rates in small molecules is proposed. The method involves measuring the difference in relaxation rates in a non-selective experiment and in one with all resonances except one of interest inverted. This procedure yields cross-relaxation rates between this nucleus and all other nuclei. These rates are independent of the effects of non-excited heteronuclei and of non-dipolar contributions and can be used to determine relative inter-proton distances. The method was tested using 7-azaindole and compared favourably with the standard NOE method for estimating proton proximities requiring less data acquisition time.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260300215
