ISSN:
1434-193X
Schlagwort(e):
Enediynes
;
Vanadium
;
C-C coupling
;
Macrocycles
;
Lactams
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
---A short synthesis of unfunctionalized lactenediyne 3 by closure of the ten-membered ring at the double bond site is reported. After failure of the known methodologies, this closure was eventually successfully achieved thanks to a highly stereoselective, vanadium(II)-mediated pinacol coupling of bis(alk-2-ynal) 7.Supporting information for this article is available on the WWW under //http://www.wiley-vch.de/contents/jc_2046/2000/99471_s.pdf or from the author.
Materialart:
Digitale Medien
