ISSN:
1434-193X
Schlagwort(e):
Dynamic combinatorial chemistry
;
Molecular recognition
;
Hydrogen bonding
;
Hydrazone isomerization
;
Barbiturate receptor
;
Chemistry
;
General Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The selection of the receptor presenting the strongest affinity for a barbiturate substrate from a dynamic combinatorial library of constituents differing in structure and conformation/configuration is described. The gradual addition of the barbiturate to an equilibrating mixture of hydrazone isomers leads to the quantitative shift towards a single species, 3, which presents highest complementarity to the substrate and yields the supramolecular entity 3:4.
Zusätzliches Material:
2 Ill.
Materialart:
Digitale Medien
