Publication Date:
1979-02-09
Description:
Incubation with specific antigen, myelin basic protein, greatly enhances the ability of guinea pig peritoneal exudate cells to transfer experimental allergic encephalomyelitis. Reproducibly successful transfers are obtained with 10(7) cells. With this relatively small number of cells, in vitro studies to determine the immunologic mechanisms involved in the disease process are now possible.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Driscoll, B F -- Kies, M W -- Alvord, E C Jr -- New York, N.Y. -- Science. 1979 Feb 9;203(4380):547-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/83676" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Antigens
;
Ascitic Fluid/*cytology/immunology
;
Cell Adhesion
;
Cell Division
;
Encephalomyelitis, Autoimmune, Experimental/immunology/*transmission
;
Exudates and Transudates/immunology
;
Guinea Pigs
;
Immunization, Passive
;
Male
;
Myelin Basic Protein/immunology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
