Publication Date:
1994-04-29
Description:
Molecular investigations of evolutionary history are being used to study subjects as diverse as the epidemiology of acquired immune deficiency syndrome and the origin of life. These studies depend on accurate estimates of phylogeny. The performance of methods of phylogenetic analysis can be assessed by numerical simulation studies and by the experimental evolution of organisms in controlled laboratory situations. Both kinds of assessment indicate that existing methods are effective at estimating phylogenies over a wide range of evolutionary conditions, especially if information about substitution bias is used to provide differential weightings for character transformations.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hillis, D M -- Huelsenbeck, J P -- Cunningham, C W -- New York, N.Y. -- Science. 1994 Apr 29;264(5159):671-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Zoology, University of Texas, Austin 78712.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8171318" target="_blank"〉PubMed〈/a〉
Keywords:
Bacteriophage T7/*genetics
;
Biological Evolution
;
Computer Simulation
;
Dentists
;
Female
;
*Genome, Viral
;
HIV/*genetics
;
HIV Envelope Protein gp120/genetics
;
HIV Infections/microbiology/transmission
;
Humans
;
Infectious Disease Transmission, Professional-to-Patient
;
Male
;
Models, Biological
;
*Phylogeny
;
Probability
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
