Publication Date:
1995-02-17
Description:
Red-green color vision is based on middle-wavelength- and long-wavelength-sensitive visual pigments encoded by an array of genes on the X chromosome. The numbers and ratios of genes in this cluster were reexamined in men with normal color vision by means of newly refined methods. These methods revealed that many men had more pigment genes on the X chromosome than had previously been suggested and that many had more than one long-wave pigment gene. These discoveries challenge accepted ideas that are the foundation for theories of normal and anomalous color vision.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Neitz, M -- Neitz, J -- EY01931/EY/NEI NIH HHS/ -- EY09303/EY/NEI NIH HHS/ -- EY09620/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1995 Feb 17;267(5200):1013-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Ophthalmology, Medical College of Wisconsin, Milwaukee 53226.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7863325" target="_blank"〉PubMed〈/a〉
Keywords:
Base Sequence
;
Blotting, Southern
;
Color Perception/*genetics
;
Color Vision Defects/genetics
;
Genes
;
Genetic Linkage
;
Humans
;
Male
;
Molecular Sequence Data
;
*Multigene Family
;
Polymerase Chain Reaction
;
Recombination, Genetic
;
Retinal Pigments/*genetics
;
*X Chromosome
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
