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Phenytoin-induced teratogenesis: a mouse model (1981)

R. H. Finnell

American Association for the Advancement of Science (AAAS)

In: Science. 211(4481): 483-4.

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Publication Date: 1981-01-30

Description: Malformations associated with the fetal hydantoin syndrome have been reproduced in a mouse model. The occurrence of these defects was correlated with maternal serum concentrations, but not with maternal or fetal genotype or the presence of a seizure disorder.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Finnell, R H -- New York, N.Y. -- Science. 1981 Jan 30;211(4481):483-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7455686" target="_blank"〉PubMed〈/a〉

Keywords: Animals ; Disease Models, Animal ; Epilepsy/drug therapy ; Female ; Mice ; Mice, Neurologic Mutants/physiology ; Phenytoin/*adverse effects ; *Teratogens

Print ISSN: 0036-8075

Electronic ISSN: 1095-9203

Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics

Published by American Association for the Advancement of Science (AAAS)

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