Publication Date:
1980-06-13
Description:
Quantitative electron microscopic autoradiography and diaminobenzidine cytochemistry provide evidence for an uptake and vesicular transport mechanism for iodine-125-labeled immunoglobulin A from plasma to bile by hepatocytes in vivo. The data confirm the existence of a hepatobiliary pathway for secretion of immunoglobulin A into the intestine and are consistent with a vesicular transport mechanism for biliary proteins within liver parenchymal cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Renston, R H -- Jones, A L -- Christiansen, W D -- Hradek, G T -- Underdown, B J -- New York, N.Y. -- Science. 1980 Jun 13;208(4449):1276-8.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375938" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Autoradiography
;
Bile/*immunology
;
Biological Transport
;
Cell Membrane/metabolism
;
Cytoplasm/metabolism
;
Immunoglobulin A/*metabolism
;
Immunoglobulin A, Secretory/*metabolism
;
Liver/immunology/*secretion
;
Male
;
Organoids/metabolism
;
Rats
;
Secretory Component/metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
