Publication Date:
1980-06-06
Description:
Feeding induced by food deprivation is accompanied by an increased production of the dopamine metabolite 3,4-dihydroxyphenylacetic acid in the brains of rats. This neurochemical change occurs in the nucleus accumbens, the posterior hypothalamus, and the amygdala but not in other dopaminergic nerve terminal fields such as the corpus striatum. These results indicate that the release of dopamine from particular groups of central neurons is increased during feeding and suggest that anatomically distinct subgroups of central dopaminergic neurons serve different roles in the regulation of food intake.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Heffner, T G -- Hartman, J A -- Seiden, L S -- New York, N.Y. -- Science. 1980 Jun 6;208(4448):1168-70.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7375926" target="_blank"〉PubMed〈/a〉
Keywords:
3,4-Dihydroxyphenylacetic Acid/metabolism
;
Amygdala/metabolism
;
Animals
;
Brain/*metabolism
;
Dopamine/*metabolism
;
*Eating
;
Food Deprivation
;
Hypothalamus/metabolism
;
Male
;
Nucleus Accumbens/metabolism
;
Putamen/metabolism
;
Rats
;
Satiation/*physiology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
