Publication Date:
1981-04-17
Description:
Nonadherent tissue culture cell lines were established from normal bone marrow of a variety of mouse strains. The lines possessed morphological and histochemical markers of the basophil/mast cell and contained committed stem cells for metachromatic cells. Their derivation from normal marrow and their lack of tumorigenicity despite long-term culture makes these cell lines potentially important for studies of the mechanisms of allergic reactions and inflammation as well as the differentiation pathways involving this subset of hematopoietic cells.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nagao, K -- Yokoro, K -- Aaronson, S A -- New York, N.Y. -- Science. 1981 Apr 17;212(4492):333-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7209531" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
*Basophils
;
*Bone Marrow Cells
;
Cell Differentiation
;
*Cell Line
;
Culture Techniques
;
Hematopoietic Stem Cells
;
Histocytochemistry
;
*Mast Cells
;
Mice
;
Mice, Inbred Strains
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
