Publication Date:
1983-03-11
Description:
Sister chromatid exchange rates increased significantly in the peripheral lymphocytes of a small group of hospital workers exposed to ethylene oxide for as little as 3.6 minutes per day regularly over a period of months. Results based on breathing zone exposure and task frequency estimates over a 6-month period for 14 workers suggest that sister chromatid exchanges are a sensitive indicator of exposure and that cumulative dose and dose rate are important predictors of sister chromatid exchange response.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yager, J W -- Hines, C J -- Spear, R C -- New York, N.Y. -- Science. 1983 Mar 11;219(4589):1221-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6828851" target="_blank"〉PubMed〈/a〉
Keywords:
Crossing Over, Genetic/*drug effects
;
Dose-Response Relationship, Drug
;
Environmental Exposure
;
Ethylene Oxide/*toxicity
;
Humans
;
Lymphocytes/*drug effects
;
Occupational Diseases/*chemically induced
;
Sister Chromatid Exchange/*drug effects
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
