Publication Date:
1984-04-20
Description:
Local rates of cerebral glucose utilization were measured in rats by the quantitative 2-deoxy-D-[14C]glucose autoradiographic method during electrical stimulation of the ventral tegmental area. Rats trained in intracranial self-stimulation showed a pattern of changes in forebrain metabolic activity distinctly different from the pattern seen in rats stimulated by the experimenter. These findings provide information about the distribution of local cerebral activity specific to reinforced instrumental behavior.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Porrino, L J -- Esposito, R U -- Seeger, T F -- Crane, A M -- Pert, A -- Sokoloff, L -- New York, N.Y. -- Science. 1984 Apr 20;224(4646):306-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6710145" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Autoradiography
;
Behavior, Animal
;
Brain/*metabolism
;
Deoxy Sugars/*metabolism
;
Deoxyglucose/*metabolism
;
Diencephalon/metabolism
;
Electric Stimulation
;
Male
;
Rats
;
Rats, Inbred Strains
;
Reinforcement (Psychology)
;
*Reward
;
Self Stimulation/*physiology
;
Telencephalon/metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
