Publication Date:
1984-04-20
Description:
A novel type D retrovirus was isolated by cocultivation of explants of fibromatous tissue from a rhesus monkey (Macaca mulatta) with immunodeficiency and retroperitoneal fibromatosis. This type D virus, isolated from a macaque with simian acquired immunodeficiency syndrome (SAIDS-D/Washington), is exogenous and is partially related to the Mason-Pfizer and the langur monkey type D viruses. The SAiDS-D virus can be distinguished from all other primate retroviruses by antigenicity and molecular hybridization. Nucleic acid hybridization studies reveal that the origin of the SAIDS-D isolate may reside in Old World monkey (subfamily Colobinae) cellular DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stromberg, K -- Benveniste, R E -- Arthur, L O -- Rabin, H -- Giddens, W E Jr -- Ochs, H D -- Morton, W R -- Tsai, C C -- N01-CO-23909/CO/NCI NIH HHS/ -- N01-CO-23910/CO/NCI NIH HHS/ -- RR00166/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1984 Apr 20;224(4646):289-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6200929" target="_blank"〉PubMed〈/a〉
Keywords:
Acquired Immunodeficiency Syndrome/microbiology/*veterinary
;
Animals
;
Antigens, Viral/immunology
;
Base Sequence
;
Cercopithecidae/genetics
;
DNA, Viral
;
*Disease Models, Animal
;
Epitopes
;
Fibroma/microbiology/*veterinary
;
Macaca mulatta/microbiology
;
Monkey Diseases/*microbiology
;
Nucleic Acid Hybridization
;
Retroperitoneal Neoplasms/microbiology/*veterinary
;
Retroviridae/classification/*isolation & purification/physiology
;
Viral Core Proteins
;
Viral Envelope Proteins/immunology
;
Viral Proteins/immunology
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
