Publication Date:
1980-08-15
Description:
Microinjection of L-glutamate into the intermediate nucleus tractus solitarii in anesthetized rats elicits hypotension, bradycardia, and apnea, simulating baroreceptor reflexes. Ablation of the nodose ganglion results in selective reduction of high-affinity uptake of L-glutanate in the nucleus tractus solitarii. L-Glutamate may be the neurotransmitter of afferent nerve fibers from arterial baroreceptors.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Talman, W T -- Perrone, M H -- Reis, D J -- New York, N.Y. -- Science. 1980 Aug 15;209(4458):813-5.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6105709" target="_blank"〉PubMed〈/a〉
Keywords:
Afferent Pathways/physiology
;
Animals
;
Blood Pressure/drug effects
;
Brain Mapping
;
Glutamates/pharmacology/*physiology
;
Heart Rate/drug effects
;
Kainic Acid/pharmacology
;
Medulla Oblongata/*physiology
;
Neurotransmitter Agents/*physiology
;
Pressoreceptors/*physiology
;
Rats
;
Reflex/drug effects
;
Respiration/drug effects
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
