Publication Date:
1979-06-15
Description:
A new C26 sterol, 22-trans-27-norcholesta-5,22-dien-3 beta-ol, was found in the urine of a 6-year-old girl, with a clinical diagnosis of congenital adrenal hyperplasia of the salt losing type, accompanied by symptoms of mixed sex anatomy and skin pigmentation. The structure of the sterol was determined by comparison with the synthetic compound. The sterol was also detected in ther serum. This appears to be the first case in which a C26 sterol has occurred in mammalia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ikekawa, N -- Fujimoto, Y -- Isiguro, M -- Suwa, S -- Hirayama, Y -- Mizunuma, H -- New York, N.Y. -- Science. 1979 Jun 15;204(4398):1223-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/451568" target="_blank"〉PubMed〈/a〉
Keywords:
Adrenocortical Hyperfunction/*urine
;
Child
;
Cholestadienols/blood/*urine
;
Female
;
Humans
;
Norsteroids/blood/urine
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
