Publication Date:
1979-07-27
Description:
Subcutaneous injection of 50 micrograms of a long-acting analog of luteinizing hormone-releasing factor on each of two successive days during mid-luteal phase in normally cycling women induced a short luteal phase and premature menstruation. These events were associated with luteolysis, as evidenced by the consistent and parallel premature decline of progesterone and estradiol levels compared with those in control cycles. This finding may prove to be useful in the prevention or interception of implantation.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Casper, R F -- Yen, S S -- New York, N.Y. -- Science. 1979 Jul 27;205(4404):408-10.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/377491" target="_blank"〉PubMed〈/a〉
Keywords:
Corpus Luteum/drug effects/*physiology
;
Estradiol/blood
;
Female
;
Follicle Stimulating Hormone/blood
;
Gonadotropin-Releasing Hormone/*analogs & derivatives
;
Humans
;
Luteal Phase/*drug effects
;
Luteinizing Hormone/blood
;
Menstruation/*drug effects
;
Progesterone/blood
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
