Publication Date:
1987-04-17
Description:
This review discusses reasons why animal cancer tests cannot be used to predict absolute human risks. Such tests, however, may be used to indicate that some chemicals might be of greater concern than others. Possible hazards to humans from a variety of rodent carcinogens are ranked by an index that relates the potency of each carcinogen in rodents to the exposure in humans. This ranking suggests that carcinogenic hazards from current levels of pesticide residues or water pollution are likely to be of minimal concern relative to the background levels of natural substances, though one cannot say whether these natural exposures are likely to be of major or minor importance.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ames, B N -- Magaw, R -- Gold, L S -- 222-Y01-ES-10066/ES/NIEHS NIH HHS/ -- CA39910/CA/NCI NIH HHS/ -- ES01896/ES/NIEHS NIH HHS/ -- New York, N.Y. -- Science. 1987 Apr 17;236(4799):271-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3563506" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Carcinogens/*classification
;
Environmental Exposure
;
Humans
;
Neoplasms/*chemically induced/epidemiology
;
Neoplasms, Experimental/pathology
;
Prognosis
;
Risk
;
United States
;
United States Environmental Protection Agency
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
