Publication Date:
1985-07-05
Description:
Glucose-6-phosphatase activity in the rat brain in vivo was estimated by measuring the differential loss of tritium and carbon-14 from the glucose pool labeled by a mixture of [2-3H]glucose and [U-14C]glucose. The results provide no evidence of significant dephosphorylation of glucose-6-phosphate and do not support the hypothesis of a futile cycle involving glucose-6-phosphatase activity in the brain.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nelson, T -- Lucignani, G -- Atlas, S -- Crane, A M -- Dienel, G A -- Sokoloff, L -- New York, N.Y. -- Science. 1985 Jul 5;229(4708):60-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2990038" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Brain/*metabolism
;
Glucose/metabolism
;
Glucose-6-Phosphatase/*metabolism
;
Glucosephosphates/*metabolism
;
Glycolysis
;
Male
;
Rats
;
Rats, Inbred Strains
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
