Publication Date:
1986-04-11
Description:
Human color vision is based on three light-sensitive pigments. The isolation and sequencing of genomic and complementary DNA clones that encode the apoproteins of these three pigments are described. The deduced amino acid sequences show 41 +/- 1 percent identity with rhodopsin. The red and green pigments show 96 percent mutual identity but only 43 percent identity with the blue pigment. Green pigment genes vary in number among color-normal individuals and, together with a single red pigment gene, are proposed to reside in a head-to-tail tandem array within the X chromosome.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nathans, J -- Thomas, D -- Hogness, D S -- New York, N.Y. -- Science. 1986 Apr 11;232(4747):193-202.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2937147" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
Animals
;
Base Sequence
;
Biological Evolution
;
Cattle
;
Cebidae
;
Cercopithecidae
;
Color
;
Color Perception/*physiology
;
DNA/metabolism
;
Drosophila melanogaster
;
Eye Proteins/genetics/physiology
;
*Genes
;
Humans
;
Molecular Sequence Data
;
Nucleic Acid Hybridization
;
Photoreceptor Cells/physiology
;
RNA, Messenger/genetics
;
Retinal Pigments/*genetics
;
Retinaldehyde/physiology
;
Rhodopsin/genetics
;
Rod Opsins
;
X Chromosome
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
