Publication Date:
2001-02-24
Description:
Important human pathogens invade and harm simple organisms. What's more, these infections require many of the same bacterial genes needed to make mammals sick. These observations suggest that even though simple organisms aren't perfect models for complex hosts such as mammals, the basic mechanisms by which bacteria establish infections in the various organisms may be similar. As a result, the work may help microbiologists identify the host proteins involved in infections, thereby providing potential new targets for antibacterial drugs.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Strauss, E -- New York, N.Y. -- Science. 2000 Dec 22;290(5500):2245-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/11188717" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Arabidopsis/*microbiology
;
Bacteria/genetics/*pathogenicity
;
Bacterial Infections/microbiology
;
Bacterial Physiological Phenomena
;
Bacterial Proteins/genetics/metabolism
;
Caenorhabditis elegans/*microbiology
;
Dictyostelium/*microbiology
;
Drosophila/genetics/immunology/*microbiology
;
Genes, Bacterial
;
Immunity, Innate
;
Plant Diseases/microbiology
;
Proteins/*physiology
;
Saccharomyces cerevisiae
;
Virulence
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
