Publication Date:
2000-07-15
Description:
Biosynthesis of many classes of secondary metabolites in plants is induced by the stress hormone jasmonate. The gene for ORCA3, a jasmonate-responsive APETALA2 (AP2)-domain transcription factor from Catharanthus roseus, was isolated by transferred DNA activation tagging. Orca3 overexpression resulted in enhanced expression of several metabolite biosynthetic genes and, consequently, in increased accumulation of terpenoid indole alkaloids. Regulation of metabolite biosynthetic genes by jasmonate-responsive AP2-domain transcription factors may link plant stress responses to changes in metabolism.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉van der Fits, L -- Memelink, J -- New York, N.Y. -- Science. 2000 Jul 14;289(5477):295-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Molecular Plant Sciences, Clusius Laboratory, Leiden University, Wassenaarseweg 64, 2333 AL, Leiden, Netherlands.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10894776" target="_blank"〉PubMed〈/a〉
Keywords:
Acetates/pharmacology
;
Angiosperms/*genetics
;
Cell Line
;
Cyclopentanes/pharmacology
;
DNA, Bacterial
;
*Gene Expression Regulation, Plant
;
Homeodomain Proteins/chemistry
;
Molecular Sequence Data
;
Nuclear Proteins/chemistry
;
Oxylipins
;
Plant Growth Regulators/pharmacology
;
Plant Proteins/chemistry/*genetics/physiology
;
Transcription Factors/chemistry/*genetics/physiology
;
Vinca Alkaloids/biosynthesis/metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
