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    American Association for the Advancement of Science (AAAS)
    Publication Date: 1999-07-27
    Description: Plants produce new appendages reiteratively from groups of stem cells called shoot apical meristems. LEAFY (LFY) and APETALA1 (AP1) are pivotal for the switch to the reproductive phase, where instead of leaves the shoot apical meristem produces flowers. Use of steroid-inducible activation of LFY demonstrated that early expression of AP1 is a result of transcriptional induction by LFY. This AP1 induction is independent of protein synthesis and occurs specifically in the tissues and at the developmental stage in which floral fate is assumed. Later expression of AP1 appears to be only indirectly affected by LFY.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Wagner, D -- Sablowski, R W -- Meyerowitz, E M -- New York, N.Y. -- Science. 1999 Jul 23;285(5427):582-4.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉California Institute of Technology, Division of Biology 156-29, Pasadena, CA 91125, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10417387" target="_blank"〉PubMed〈/a〉
    Keywords: Arabidopsis/*genetics/growth & development/metabolism ; *Arabidopsis Proteins ; Cell Nucleus/metabolism ; Dexamethasone/pharmacology ; Gene Expression Regulation, Plant ; Genes, Plant ; Homeodomain Proteins/*genetics/metabolism ; In Situ Hybridization, Fluorescence ; MADS Domain Proteins ; Meristem/genetics/metabolism ; Mutation ; Plant Proteins/biosynthesis/*genetics/*metabolism ; Plant Structures/genetics/growth & development/metabolism ; Promoter Regions, Genetic ; RNA, Plant/genetics/metabolism ; Recombinant Fusion Proteins/metabolism ; Trans-Activators/genetics/*metabolism ; *Transcription Factors ; *Transcriptional Activation ; Transformation, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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