Publication Date:
1999-06-26
Description:
Ethylene regulates plant growth, development, and responsiveness to a variety of stresses. Cloning of the Arabidopsis EIN2 gene identifies a central component of the ethylene signaling pathway. The amino-terminal integral membrane domain of EIN2 shows similarity to the disease-related Nramp family of metal-ion transporters. Expression of the EIN2 CEND is sufficient to constitutively activate ethylene responses and restores responsiveness to jasmonic acid and paraquat-induced oxygen radicals to mutant plants. EIN2 is thus recognized as a molecular link between previously distinct hormone response pathways. Plants may use a combinatorial mechanism for assessing various stresses by enlisting a common set of signaling molecules.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Alonso, J M -- Hirayama, T -- Roman, G -- Nourizadeh, S -- Ecker, J R -- New York, N.Y. -- Science. 1999 Jun 25;284(5423):2148-52.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia, PA 19104-6018, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/10381874" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
Arabidopsis/chemistry/genetics/growth & development/*physiology
;
*Arabidopsis Proteins
;
Carrier Proteins/chemistry
;
*Cation Transport Proteins
;
Cloning, Molecular
;
Cyclopentanes/metabolism/pharmacology
;
*Defensins
;
Ethylenes/*metabolism/pharmacology
;
Gene Expression Regulation, Plant
;
Genes, Plant
;
Genetic Complementation Test
;
Herbicides/pharmacology
;
*Iron-Binding Proteins
;
Membrane Proteins/chemistry/genetics/*physiology
;
Microsomes/metabolism
;
Molecular Sequence Data
;
Mutation
;
Nuclear Proteins/physiology
;
Oxylipins
;
Paraquat/pharmacology
;
Plant Growth Regulators/*metabolism/pharmacology
;
Plant Proteins/chemistry/genetics/*physiology
;
Plants, Genetically Modified
;
Protein Biosynthesis
;
Protein Structure, Secondary
;
Receptors, Cell Surface/chemistry/genetics/*physiology
;
*Signal Transduction
;
*Transcription Factors
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
