Publication Date:
2013-02-23
Description:
The scale-up of antiretroviral therapy (ART) is expected to raise adult life expectancy in populations with high HIV prevalence. Using data from a population cohort of over 101,000 individuals in rural KwaZulu-Natal, South Africa, we measured changes in adult life expectancy for 2000-2011. In 2003, the year before ART became available in the public-sector health system, adult life expectancy was 49.2 years; by 2011, adult life expectancy had increased to 60.5 years--an 11.3-year gain. Based on standard monetary valuation of life, the survival benefits of ART far outweigh the costs of providing treatment in this community. These gains in adult life expectancy signify the social value of ART and have implications for the investment decisions of individuals, governments, and donors.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860268/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3860268/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Bor, Jacob -- Herbst, Abraham J -- Newell, Marie-Louise -- Barnighausen, Till -- 097410/Wellcome Trust/United Kingdom -- 1R01MH083539-01/MH/NIMH NIH HHS/ -- R01 HD058482-01/HD/NICHD NIH HHS/ -- R01 MH083539/MH/NIMH NIH HHS/ -- Wellcome Trust/United Kingdom -- New York, N.Y. -- Science. 2013 Feb 22;339(6122):961-5. doi: 10.1126/science.1230413.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Post Office Box 198, Mtubatuba, KwaZulu-Natal 3935, South Africa. jbor@hsph.harvard.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/23430655" target="_blank"〉PubMed〈/a〉
Keywords:
Adult
;
Anti-HIV Agents/economics/*therapeutic use
;
*Antiretroviral Therapy, Highly Active/economics
;
Cohort Studies
;
Cost-Benefit Analysis
;
Delivery of Health Care
;
Female
;
HIV Infections/*drug therapy/*mortality
;
Humans
;
Kaplan-Meier Estimate
;
*Life Expectancy/trends
;
Male
;
Middle Aged
;
*Mortality
;
Prevalence
;
Public Sector
;
*Rural Health
;
South Africa/epidemiology
;
Value of Life
;
Young Adult
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
