Publication Date:
2009-08-29
Description:
〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Restuccia, David F -- Hemmings, Brian A -- New York, N.Y. -- Science. 2009 Aug 28;325(5944):1083-4. doi: 10.1126/science.1179972.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, CH-4058 Basel, Switzerland.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19713516" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Substitution
;
Animals
;
Antineoplastic Agents/therapeutic use
;
Apoptosis
;
Cell Line, Tumor
;
Cell Membrane/metabolism
;
Enzyme Activation
;
Humans
;
Mice
;
Mice, Nude
;
Mutation
;
Neoplasms/drug therapy/*metabolism/pathology
;
Protein Transport
;
Proto-Oncogene Proteins c-akt/chemistry/genetics/*metabolism
;
RNA Interference
;
*Signal Transduction
;
Sirolimus/analogs & derivatives/therapeutic use
;
TNF Receptor-Associated Factor 6/antagonists & inhibitors/genetics/*metabolism
;
Ubiquitin-Protein Ligases/metabolism
;
Ubiquitination
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics