Publication Date:
2009-03-28
Description:
Little is known about the genetic contribution to individual differences in neural networks subserving cognition function. In this functional magnetic resonance imaging (fMRI) twin study, we found a significant genetic influence on brain activation in neural networks supporting digit working memory tasks. Participants activating frontal-parietal networks responded faster than individuals relying more on language-related brain networks. There were genetic influences on brain activation in language-relevant brain circuits that were atypical for numerical working memory tasks as such. This suggests that differences in cognition might be related to brain activation patterns that differ qualitatively among individuals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Koten, Jan Willem Jr -- Wood, Guilherme -- Hagoort, Peter -- Goebel, Rainer -- Propping, Peter -- Willmes, Klaus -- Boomsma, Dorret I -- New York, N.Y. -- Science. 2009 Mar 27;323(5922):1737-40. doi: 10.1126/science.1167371.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Section Neuropsychology, RWTH Aachen University, Germany. jan.koten@gmx.de〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/19325117" target="_blank"〉PubMed〈/a〉
Keywords:
Adult
;
Brain/*physiology
;
Brain Mapping
;
Cerebrum/physiology
;
*Cognition
;
*Genes
;
Humans
;
Magnetic Resonance Imaging
;
Male
;
Mathematical Concepts
;
*Memory, Short-Term
;
Nerve Net/*physiology
;
Siblings
;
Twins, Monozygotic
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
