Publication Date:
2008-09-13
Description:
Object recognition is challenging because each object produces myriad retinal images. Responses of neurons from the inferior temporal cortex (IT) are selective to different objects, yet tolerant ("invariant") to changes in object position, scale, and pose. How does the brain construct this neuronal tolerance? We report a form of neuronal learning that suggests the underlying solution. Targeted alteration of the natural temporal contiguity of visual experience caused specific changes in IT position tolerance. This unsupervised temporal slowness learning (UTL) was substantial, increased with experience, and was significant in single IT neurons after just 1 hour. Together with previous theoretical work and human object perception experiments, we speculate that UTL may reflect the mechanism by which the visual stream builds and maintains tolerant object representations.〈br /〉〈br /〉〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307055/" target="_blank"〉〈img src="https://static.pubmed.gov/portal/portal3rc.fcgi/4089621/img/3977009" border="0"〉〈/a〉 〈a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307055/" target="_blank"〉This paper as free author manuscript - peer-reviewed and accepted for publication〈/a〉〈br /〉〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Li, Nuo -- DiCarlo, James J -- R01 EY014970/EY/NEI NIH HHS/ -- R01 EY014970-01A1/EY/NEI NIH HHS/ -- R01-EY014970/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 2008 Sep 12;321(5895):1502-7. doi: 10.1126/science.1160028.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/18787171" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
*Form Perception
;
*Learning
;
Macaca mulatta
;
Male
;
Models, Neurological
;
Neuronal Plasticity
;
Neurons/*physiology
;
Saccades
;
Temporal Lobe/*physiology
;
Visual Cortex/*physiology
;
*Visual Perception
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
