Publication Date:
2006-10-14
Description:
Previous studies have suggested that the minimal cellular genome could be as small as 400 kilobases. Here, we report the complete genome sequence of the psyllid symbiont Carsonella ruddii, which consists of a circular chromosome of 159,662 base pairs, averaging 16.5% GC content. It is by far the smallest and most AT-rich bacterial genome yet characterized. The genome has a high coding density (97%) with many overlapping genes and reduced gene length. Genes for translation and amino acid biosynthesis are relatively well represented, but numerous genes considered essential for life are missing, suggesting that Carsonella may have achieved organelle-like status.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nakabachi, Atsushi -- Yamashita, Atsushi -- Toh, Hidehiro -- Ishikawa, Hajime -- Dunbar, Helen E -- Moran, Nancy A -- Hattori, Masahira -- New York, N.Y. -- Science. 2006 Oct 13;314(5797):267.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Environmental Molecular Biology Laboratory, RIKEN, Wako, Saitama 351-0198, Japan. bachi@email.arizona.edu〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/17038615" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acids/biosynthesis
;
Animals
;
Base Composition
;
Chromosomes, Bacterial
;
DNA, Bacterial/chemistry/genetics
;
Gammaproteobacteria/*genetics/physiology
;
*Genes, Bacterial
;
Genes, Overlapping
;
Genes, rRNA
;
*Genome, Bacterial
;
Hemiptera/genetics/*microbiology/physiology
;
Molecular Sequence Data
;
Open Reading Frames
;
RNA, Transfer/genetics
;
Sequence Analysis, DNA
;
*Symbiosis
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
