Publication Date:
2005-05-14
Description:
The origin of the Andaman "Negrito" and Nicobar "Mongoloid" populations has been ambiguous. Our analyses of complete mitochondrial DNA sequences from Onges and Great Andaman populations revealed two deeply branching clades that share their most recent common ancestor in founder haplogroup M, with lineages spread among India, Africa, East Asia, New Guinea, and Australia. This distribution suggests that these two clades have likely survived in genetic isolation since the initial settlement of the islands during an out-of-Africa migration by anatomically modern humans. In contrast, Nicobarese sequences illustrate a close genetic relationship with populations from Southeast Asia.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Thangaraj, Kumarasamy -- Chaubey, Gyaneshwer -- Kivisild, Toomas -- Reddy, Alla G -- Singh, Vijay Kumar -- Rasalkar, Avinash A -- Singh, Lalji -- New York, N.Y. -- Science. 2005 May 13;308(5724):996.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Centre for Cellular and Molecular Biology, Hyderabad-500 007, India.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15890876" target="_blank"〉PubMed〈/a〉
Keywords:
Africa
;
Asia
;
Asia, Southeastern
;
Chromosomes, Human, Y/genetics
;
DNA, Mitochondrial/*genetics
;
Emigration and Immigration
;
Ethnic Groups/*genetics
;
Founder Effect
;
Genetic Drift
;
Genetics, Population
;
Geography
;
Haplotypes
;
Humans
;
India
;
Mutation
;
Phylogeny
;
Sequence Analysis, DNA
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
