Publication Date:
2005-02-15
Description:
The thymus is the nursery where T cell precursors mature into T cells of the and lineages. In a Perspective, Rothenberg discusses intriguing findings that reveal a new level of regulation in the thymus (Silva-Santos et al.). Apparently, double-positive T cells that are destined to mature into T cells directly regulate the development of the T-cell lineage through the production of lymphotoxin and the action of a transcription factor called RORt.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Rothenberg, Ellen V -- New York, N.Y. -- Science. 2005 Feb 11;307(5711):858-859.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/15708841" target="_blank"〉PubMed〈/a〉
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
