Publication Date:
2018-08-10
Description:
Sensors, Vol. 18, Pages 2607: Fabrication of a Urea Biosensor for Real-Time Dynamic Fluid Measurement Sensors doi: 10.3390/s18082607 Authors: Kyunghee Kim Jeongeun Lee Bo Mi Moon Ye Been Seo Chan Hum Park Min Park Gun Yong Sung In this study, a portable urea sensor that monitors the urea concentration in flow conditions was fabricated. We propose an electrochemical sensor that continually measures the urea concentration of samples flowing through it at a constant flow rate in real time. For the electrochemical sensing, a porous silk fibroin membrane with immobilized urease was mounted in a polydimethylsiloxane (PDMS) sensor housing. The fabricated urea sensor elicited linear current–concentration characteristics in the clinically significant concentration range (0.1–20 mM) based on peritoneal dialysis. The sensor maintained the linear current–concentration characteristics during operation in flow conditions.
Electronic ISSN:
1424-8220
Topics:
Chemistry and Pharmacology
,
Electrical Engineering, Measurement and Control Technology
