Publication Date:
2016-10-19
Description:
Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes Nature Communications, Published online: 18 October 2016; doi:10.1038/ncomms13223 Leishmania donovani is a protozoan parasite that can cause fatal infections in humans. Here the authors present a high resolution cryoEM structure of the L. donovani 80S ribosome and compare it to its human counterpart to provide insight into the basis for drug selectivity towards this eukaryotic parasite.
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics