Publication Date:
2015-12-10
Description:
: High-throughput sequencing technologies survey genetic variation at genome scale and are increasingly used to study the contribution of rare and low-frequency genetic variants to human traits. As part of the Cohorts arm of the UK10K project, genetic variants called from low-read depth (average 7 x ) whole genome sequencing of 3621 cohort individuals were analysed for statistical associations with 64 different phenotypic traits of biomedical importance. Here, we describe a novel genome browser based on the Biodalliance platform developed to provide interactive access to the association results of the project. Availability and implementation : The browser is available at http://www.uk10k.org/dalliance.html . Source code for the Biodalliance platform is available under a BSD license from http://github.com/dasmoth/dalliance , and for the LD-display plugin and backend from http://github.com/dasmoth/ldserv . Contact : ns6@sanger.ac.uk or thomas@biodalliance.org Supplementary information : Supplementary data are available at Bioinformatics online.
Print ISSN:
1367-4803
Electronic ISSN:
1460-2059
Topics:
Biology
,
Computer Science
,
Medicine
