Publikationsdatum:
2015-10-22
Beschreibung:
Article The elimination of latently infected cells is a sought after goal in the treatment of HIV-1 infections. Here the authors develop an approach to eliminate latently HIV-1 infected cells by using an immunomodulatory protein, which can activate viral gene expression in these cells and direct T lymphocytes to lyse them in vitro . Nature Communications doi: 10.1038/ncomms9447 Authors: Amarendra Pegu, Mangaiarkarasi Asokan, Lan Wu, Keyun Wang, Jason Hataye, Joseph P. Casazza, Xiaoti Guo, Wei Shi, Ivelin Georgiev, Tongqing Zhou, Xuejun Chen, Sijy O’Dell, John-Paul Todd, Peter D. Kwong, Srinivas S. Rao, Zhi-yong Yang, Richard A. Koup, John R. Mascola, Gary J. Nabel
Digitale ISSN:
2041-1723
Thema:
Biologie
,
Chemie und Pharmazie
,
Allgemeine Naturwissenschaft
,
Physik