Publication Date:
2015-10-11
Description:
Article Directed cell migration in weak electric fields is known as galvanotaxis, but the cellular sensor and mechanism is not known. Here Nakajima et al. identify inwardly rectifying K + channel Kir4.2 as an important mediator of galvanotaxis, that depends on the cytoplasmic distribution of intracellular polyamines. Nature Communications doi: 10.1038/ncomms9532 Authors: Ken-ichi Nakajima, Kan Zhu, Yao-Hui Sun, Bence Hegyi, Qunli Zeng, Christopher J. Murphy, J. Victor Small, Ye Chen-Izu, Yoshihiro Izumiya, Josef M. Penninger, Min Zhao
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics