Publication Date:
2015-08-08
Description:
Article Mutations in the transcription factor MEF2B are found in diffuse large B-cell lymphoma. In this study, the authors map the DNA-binding sites of the transcription factor in cells in vitro and find that the mutations decrease the ability of MEF2B to activate transcription. Nature Communications doi: 10.1038/ncomms8953 Authors: Julia R. Pon, Jackson Wong, Saeed Saberi, Olivia Alder, Michelle Moksa, S. -W. Grace Cheng, Gregg B. Morin, Pamela A. Hoodless, Martin Hirst, Marco A. Marra
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics