Publication Date:
2013-11-30
Description:
Article Induction of protective immunity mediated by CD8 + T cells has been a long sought goal in vaccinology. Here, Ewer et al. report induction of protective efficacy against Plasmodium falciparum malaria in a phase IIa prime-boost vaccine trial where efficacy correlates strongly with induced CD8 T-cell responses. Nature Communications doi: 10.1038/ncomms3836 Authors: Katie J. Ewer, Geraldine A. O’Hara, Christopher J. A. Duncan, Katharine A. Collins, Susanne H. Sheehy, Arturo Reyes-Sandoval, Anna L. Goodman, Nick J. Edwards, Sean C. Elias, Fenella D. Halstead, Rhea J. Longley, Rosalind Rowland, Ian D. Poulton, Simon J. Draper, Andrew M. Blagborough, Eleanor Berrie, Sarah Moyle, Nicola Williams, Loredana Siani, Antonella Folgori, Stefano Colloca, Robert E. Sinden, Alison M. Lawrie, Riccardo Cortese, Sarah C. Gilbert, Alfredo Nicosia, Adrian V. S. Hill
Electronic ISSN:
2041-1723
Topics:
Biology
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Chemistry and Pharmacology
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Natural Sciences in General
,
Physics