Publication Date:
2013-10-25
Description:
Article Mutations in the haemagglutinin of H5N1 avian influenza viruses confer transmissibility in ferrets. Here, Wilker et al . show that while within host variability is high, transmitted virus diversity is low suggesting a genetic bottleneck acts during transmission, driven by selection on haemagglutinin genes. Nature Communications doi: 10.1038/ncomms3636 Authors: Peter R. Wilker, Jorge M. Dinis, Gabriel Starrett, Masaki Imai, Masato Hatta, Chase W. Nelson, David H. O’Connor, Austin L. Hughes, Gabriele Neumann, Yoshihiro Kawaoka, Thomas C. Friedrich
Electronic ISSN:
2041-1723
Topics:
Biology
,
Chemistry and Pharmacology
,
Natural Sciences in General
,
Physics