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Handheld Fluorescence Resonance Energy Transfer (FRET)-Aptamer Sensor for Bone Markers (2015)

Bruno, John G.

In: CASI

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Publication Date: 2019-07-12

Description: Astronauts lose significant bone mass during lengthy space flights. NASA wishes to monitor this bone loss in order to develop nutritional and exercise countermeasures. Operational Technologies Corporation (OpTech) has developed a handheld device that quantifies bone loss in a spacecraft environment. The innovation works by adding fluorescent dyes and quenchers to aptamers to enable pushbutton, one-step bind-and-detect FRET assays that can be freeze-dried, rehydrated with body fluids, and used to quantify bone loss.

Keywords: Aerospace Medicine

Type: An Overview of SBIR Phase 2 Physical Sciences and Biomedical Technologies in Space; 4; NASA/TM-2015-218857

Format: application/pdf

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