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Polyphosphorylation and non-enzymatic template-directed ligation of oligonucleotides (2000)

Bada, J. L. ; Orgel, L. E. ; Gao, K.

In: Other Sources

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Publication Date: 2011-08-24

Description: Oligonucleotide 5'-polyphosphates are formed under potentially prebiotic conditions from oligonucleotide 5'-phosphates and sodium trimetaphosphate. Oligonucleotides activated as polyphosphates undergo template-directed ligation. We believe that these reactions could have produced longer oligonucleotide products from shorter substrates under prebiotic conditions.

Keywords: Exobiology

Type: Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life (ISSN 0169-6149); Volume 30; 1; 45-51

Format: text

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