Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
The @journal of eukaryotic microbiology
44 (1997), S. 0
ISSN:
1550-7408
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Biology
Notes:
. We used a photoactivatable fluid-phase marker to isolate a new collection of thermosensitive endocytosis mutants in the cellular slime mold Dicfyostelium discoideum. All the strains were thermosensitive for growth on bacteria or axenic medium at 27° C. Initial rates of endocytosis rapidly decreased upon incubation at the restrictive temperature, but surprisingly most of the strains showed a transient recovery of activity with prolonged exposure to 27° C. Endocytosis and exocytosis activities were uncoupled for some of the cell lines at 27° C whereas the others had to be shifted to 29° C. Further molecular analysis of these mutants could lead to the discovery of new proteins involved in endocytosis and its regulation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1550-7408.1997.tb05969.x
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