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The effect of probiotic bacteria on the adhesion of pathogens to human intestinal mucus (1999)

Tuomola, Elina M ; Ouwehand, Arthur C ; Salminen, Seppo J

Oxford, UK : Blackwell Publishing Ltd

FEMS immunology and medical microbiology 26 (1999), S. 0

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ISSN: 1574-695X

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology , Medicine

Notes: Human intestinal glycoproteins extracted from faeces were used as a model for intestinal mucus to investigate adhesion of pathogenic Escherichia coli and Salmonella strains, and the effect of probiotics on this adhesion. S-fimbriated E. coli expressed relatively high adhesion in the mucus model, but the other tested pathogens adhered less effectively. Probiotic strains Lactobacillus GG and L. rhamnosus LC-705 as well as a L. rhamnosus isolated from human faeces were able to slightly reduce S-fimbria-mediated adhesion. Adhesion of S. typhimurium was significantly inhibited by probiotic L. johnsonii LJ1 and L. casei Shirota. Lactobacillus GG and L. rhamnosus (human isolate) increased the adhesion of S. typhimurium suggesting that the pathogen interacts with the probiotic.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1574-695X.1999.tb01381.x

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